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Sometimes, massaging on topical ointments can help reduce pain and inflammation. Stickel F, Seitz HK. The review included one study of 220 people with knee osteoarthritis, a degenerative "wear-and-tear" joint condition. Like any new treatment, discontinue use if any irritation occurs. NCCIH. Don't use comfrey products if you have or are at risk of having liver disease, cancer, or are taking any medication that affects the liver since it may increase the risk of liver toxicity. doi:10.1002/ptr.4612, Salehi B, Sharopov F, Boyunegmez Tumer T, et al. 1. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Credit Solution Experts Incorporated offers quality business credit building services, which includes an easy step-by-step system designed for helping clients build their business credit effortlessly. First, make the comfrey root tincture by combining the dried comfrey root and alcohol in a sterilized, dry, glass pint jar. Huxtable RJ, Awang DV. Comfrey is a fast-growing plant whose leaves and roots have been used historically for wound healing and other conditions. Other prescription medicines that may harm the liver include: Some supplements may also harm the liver, including: It is essential to carefully read a supplement's ingredient list and nutrition facts panel to know which ingredients and how much of each ingredient is included. Avoid taking comfrey orally (by mouth). As a Licensed Massage Therapist for fifteen years, I have noticed that back pain can be caused by a variety of reasons and can be very debilitating. Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. It can grow up to 5 feet tall. Koll R, Klingenburg S. [Therapeutic characteristance and tolerance of topical comfrey preparations. J Pharmacopuncture 2021;24(4):196-205. Label with the ingredients and date made. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. Links to external sites are for informational purposes only. Call your doctor for medical advice about . Comfrey oil should be applied topically to parts of the body where you have muscular pain or discomfort. In a randomized, double-blind, placebo-controlled trial, 220 patients with knee osteoarthritis used either a commercial topical comfrey root extract or a placebo. This soothing blend of herbal oils contains Comfrey (also known as Knitbone) and Eucalyptus Oil. Comfrey is an herb in the Boraginaceae family and has small purple flowers. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Molecules. Br J Sports Med. View abstract. No comments. Resuscitation 2008;76(3):323-324. Do not use this product if you have a sensitivity to any of the ingredients. We comply with the HONcode standard for trustworthy health information. The warm weather has a way of encouraging us to get outside and move our bodies more. After the tincture is made, then you can whip up the fabulous joint and muscle cream! Glass bowl with a lid Affiliate links are shared throughout the website and the Herbal Academy may receive compensation if you make a purchase with these links. Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: Results of a double-blind, randomised, placebo controlled, multicentre trial. 2004;154(21-22):498-507. root extraction help ease aching joints and muscles? Kuera, M., Barna, M., Horek, O., Kovrikov, J., & Kuera, A. comfrey: [noun] any of a genus (Symphytum) of perennial herbs of the borage family with coarse hairy entire leaves and flowers in one-sided racemes. Available at: https://www.cfsan.fda.gov/~dms/dspltr06.html. Penetration of lycopsamine from a comfrey ointment through human epidermis. Comfrey. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 2758955. Phytomedicine. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. Comfrey may be used topically as a cream, ointment, salve, or paste. Comfrey has been used medicinally for at least 2000 years for various conditions, including bone fractures, ulcers, and gout. Contact your doctor or pharmacist if you have any questions before use. Undergoingmassage or taking up yoga may help alleviate pain and help people with back or joint problems function more easily. Stam, C., Bonnet, M. S., & van Haselen, R. A. Using a combination product makes it challenging to know how much of the beneficial effect came from comfrey alone. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. To reduce the risk of side effects, never apply comfrey cream to broken skin or open wounds as it may be more highly absorbed by the body. Giannetti, B. M., Staiger, C., Bulitta, M., and Predel, H. G. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo controlled, multicentre trial. Comfrey is avoided on cuts or puncture wounds for this reason. Here's 10 things essential oils are great for. Comfrey contains chemicals that cause serious liver damage when taken by mouth. Taking comfrey along with a medication that can harm the liver might increase the risk of liver damage. It produces clusters of purple, blue, and white flowers, and it's famous for its long . View abstract. Comfrey contains chemicals that can cause liver damage, lung problems, or cancer. This perennial can grow up to 4-feet tall. View abstract. Some of these components are thought to speed up wound healing by stimulating new cell growth. Information from this source is evidence-based and objective, and without commercial influence. Looks like you may need to upgrade your browser We're sorry, we no longer support the web browser that you are using Understand comfreys contraindications before using it. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). Consult your healthcare provider before using. In a small study with 30 subjects, lower back pain from exercise was reduced with an ointment containing comfrey. International Journal of Pediatrics and Adolescent Medicine, (4), 135-141. https://doi.org/10.1016/j.ijpam.2018.11.002. Finally, well warn of any side effects associated with comfrey oil. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Comfrey is changed and broken down by the liver. 2012;101(4):211-216. Comfrey ( Symphytum officinale) is an attractive ornamental plant used in gardening and medicine. Do not use more of this product than is recommended on the label. This information may not fit your specific health circumstances. Whenselecting a brand of supplements, look for products certified by Consumer Labs, the U.S.Pharmacopeia, or NSF. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. Pyrrolizidine poisoning. Comfrey's original name, knitbone, derives from the external use of poultices of its leaves and roots to heal burns, sprains, swelling, and bruises. Using different formulations together increases the risk of an overdose. Learn more in. Osteoarthritis Cartilage. Drug class: Herbal products. View abstract. Drug-induced liver injury. Definitely do not use during pregnancy or nursing, with infants, and if you have liver or kidney disease. Pabst H, Schaefer A, Staiger C, Junker-samek M, Predel HG. Symphytum officinale), store bought or via recipe, above. More research is needed. Comfrey (Symphytum officinale) is a plant with yellow or purple flowers found in Europe, Asia, and North America. Recent studies have suggested topical benefits, but more research is needed. However, even if supplements are third-party tested, that doesn't mean they are necessarily safe for all or effective in general. Follow all directions on the product label and package. It should never be taken by mouth. Jurcu, R., & Jurcu, I. After 7 years in this role and a further year working as a drug safety officer in the pharmaceutical industry, Bhupesh joined Holland &Barrett as a Senior Regulatory Affairs Associate in 2019. 2758955. Wien.Med.Wochenschr. Frost R, Macpherson H, O'meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). 2020;142:104519. Topically, comfrey root and leaf extracts have been traditionally used for bruises, sore muscles and joints, sprains, mild wounds, and gout (Natural Medicines, 2020). The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). Using a supplement like comfrey may have potential side effects. The Food and Drug Administration (FDA) released an advisory in July 2001 recommending that comfrey products be removed from the market because of cases of hepatic veno-occlusive disease. View abstract. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial. Comfrey has been used in alternative medicine as a possibly effective aid in treating back pain, osteoarthritis, or tenderness and swelling caused by a sprain injury. Please read the Topical Use Safety section of this article (above) before using. View abstract. 2004;11(6):470-477. Br.J Sports Med. This site uses cookies to improve your experience. 6 Healing Benefits of Comfrey. Apply a small amount (not to exceed a teaspoon) topically 2-3x/day for up to 2 weeks. 2017;83:1-4. Comfrey might harm the liver. (2004). It has bell-shaped red-violet or yellowish flowers. Other herbal supplements that may have benefits for back pain include: Some other supplements that may be useful for osteoarthritis are: Back pain is often treated with medication such as over-the-counter pain relievers. Set on a sunny windowsill and shake once a day for 2-4 weeks. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. Book your free, one-to-one online consultation with one of our qualified advisors. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., and Staiger, C. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study. It is easily absorbed to leave your skin feeling fresh, soft and radiant. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. We currently have no information for COMFREY overview. However, comfrey can also contain toxic substances called pyrrolizidine alkaloids that cause liver damage, cancer, and death. 2013;163(3-4):58-64. It's typically only used in small amounts for a very short period. The first European settlers of America considered comfrey so indispensable, they carried it on their journey across the Atlantic in the 1600s.2. Allow the oil mixture to cool until it reaches room temperature, which could take 8-12 hours. Complement Ther Clin Pract. Yield: Approximately 5 cups of whipped lotion. A review of 26 clinical trials concluded that mild skin reactions were the most common side effects of comfrey creams used in the studies. This is memorable if you have worked with it, and some use this quality to remember comfreys centuries-long useapplying comfrey over bones, bruises, sprains, and minor wounds with the intention to support mending! Browse our Sports Hub, Buy 1 get 1 Half Price on Vitamins & Supplements, Buy 1 get 1 Half Price gut health supplements, Contains Comfrey known for its healing properties, Symptomatic treatment of minor sprains and bruises. Although not examined in clinical trials, comfrey may possess antifungal and anticancer activity. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. Comfrey shouldn't be used in any form during pregnancy or nursing due to the risk of liver damage to infants. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. It is called knitbone or boneset, referring to the bone-like growth of its roots. Pour into bowl /jug big enough for all ingredients and safe for the mixer. Aust.Fam.Physician 2008;37(4):235-236. Skip the missed dose if it is almost time for your next scheduled dose. Sowa I, Paduch R, Strzemski M, et al. Aust.J Physiother. Preclinical studies suggest that oral comfrey has antiproliferative effects , and a topical formulation showed wound healing properties . Although topical comfrey has been used for this indication, there's little evidence that it helps and can pose a big risk for nursing babies. Comfrey root extracts have been used by herbalists and in folk traditions for centuries to soothe aches and pains. Be sure to choose organic carrier oils and essential oils when possible. J Pharm.Belg. Consult with a licensed healthcare professional before using any herbal/health supplement. Save the remaining liquid alcohol portion. J Chiropr Med. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). One study followed 142 patients with ankle sprains. When considering the use of herbal supplements, seek the advice of your doctor. 2012;62(6):285-289. Symphytum officinale L, S. asperum Lepechin, S. tuberosum L, Symphytum x uplandicum Nyman. Comfrey is not recommended for children under three years old, as it's not been studied in that population. Complement Ther Med. After the consistency begins to thicken, turn the mixer up a little bit. Metabolism, genotoxicity, and carcinogenicity of comfrey. Set aside cup for the cream recipe and store the rest in a glass jar. Herbal drugs and phytopharmaceuticals. Palestrica of the Third Millennium Civilization & Sport, 14(3). In a randomized multicenter study with 164 ankle sprain patients, swelling and pain were improved more successfully using a comfrey root extract compared to a diclofenac gel (Predel et al., 2005). Whether youre familiar with it or not, this unusual herbal remedy is definitely worth knowing more about. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination. Complementary Health Approaches for Chronic Pain: What the Science Says. The plant leaves have a lower concentration of PAs than the roots. The internal or extensive topical use of comfrey cannot be recommended because of numerous reports of liver damage. 2012;20(11):1209-16. doi:10.1016/j.joca.2012.07.019, Zago LR, Prado K, Benedito VL, Pereira MM. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. What is niacinamide? Comfrey cream, an topical herbal product, is thought to reduce inflammation and pain when applied to the skin. Regul Toxicol Pharmacol. (2004). Discontinue use if a rash develops. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Comfrey is generally considered unsafe, with numerous toxicological effects in animals and humans. Turn off heat and give it a good stir. Comfrey is a shrub that grows in parts of Europe, Asia, and North America. View abstract. Wichtl, M. (2004). Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. These have a lower risk of serious side effects like liver damage. Comfrey is an herb in the Boraginaceae family and has small purple flowers. This is because only a small amount of the pyrrolizidine alkaloids are absorbed through the skin (Jedlinszki et al., 2017). Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Remove from heat. Thank you, {{form.email}}, for signing up. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. If your healthcare provider recommends it, make sure to use it on intact skin for a small amount of time, and be careful that infants do not ingest it. There is no daily recommended allowance for comfrey, sold in creams, ointments, gels, and salves. Copyright Holland & Barrett Retail Limited, 2022. This site uses cookies to improve your experience. An ankle sprain can come out of nowhere and cause a lot of pain, limitations, and regret until it is healed. 2010;44(9):637-41. doi:10.1136/bjsm.2009.058677, Cameron M, Chrubasik S. Topical herbal therapies for treating osteoarthritis. What Are the Side Effects of Comfrey Cream? When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. Symphytum species: A comprehensive review on chemical composition, food applications and phytopharmacology. OTHER NAME(S): Ass Ear, Black Root, Blackwort, Bruisewort, Common. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. , 43 volunteers with osteoarthritis used either a topical cream containing comfrey, tannic acid, and eucalyptus or a placebo cream 3x/ day for 6 weeks. Rad. Avoid comfrey with certain medical conditions, such as liver disease. Laslett, L. L., Quinn, S. J., Darian-Smith, E., Kwok, M., Fedorova, T., Korner, H., Steels, E., March, L., and Jones, G. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Those who used the comfrey ointment experienced improvements in pain, mobility, and quality of life. Dosage: How Much Comfrey Cream Should I Use? Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. What Happens If I Use Too Much Comfrey Cream? Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. 211727395. View abstract. View abstract. This was compared to 37.8% in the placebo group. how to become a school board member in florida ocean deck band schedule Verywell Health's content is for informational and educational purposes only. Buy 1 get 1 Half Price | Plus an extra 20% off 30, Shop buy 1 get 1 half price on all gut health products, Looking for fitness advice & inspiration this New Year? In Western Europe, comfrey has been used topically for treating inflammatory disorders such as arthritis, gout, and thrombophlebitis, and internally for treating diarrhea. It contains chemicals that are poisonous. The most common over-the-counter medication that can be toxic to the liver is acetaminophen (Tylenol). randomized double-blind study of 278 patients with fresh abrasions, a. topical preparation containing a 10% comfrey leaf extraction applied for 2-3 days reduced wound healing time of adults and children without side effects (Barna et al., 2012). Phytother Res. Generic name: comfrey [COM-free] Efficacy of a comfrey root (Symphyti offic. When buying commercial brands, seek those that have had the pyrrolizidine alkaloids removed, if possible. It contains chemicals that are poisonous. Available for Android and iOS devices. Wound-healing effects of a symphytum herb extract cream (. The study involved 43 patients with knee osteoarthritis and a six-week treatment period. All rights reserved. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. (21), 498-507. https://link.springer.com/article/10.1007/s10354-004-0114-8, Natural Medicines (2020). (2001). When the root is boiled in water, it forms a sticky, glue-like paste. Researchers have found it does seem to reduce pain in some conditions, including back pain, osteoarthritis, and ankle sprains. Natural Standard. byBhupesh Panchal, Senior Regulatory Affairs Associate, Comfrey oil is a herbal oil that moisturises skin, and thats been used as a healing herb for a long time.1, Since at least the 4th century, people have used comfrey medicinally. Do not use different forms (tablets, liquid, tincture, teas, etc) of comfrey at the same time without medical advice. Registered in England: company no. Jedlinszki N, Balzs B, Csnyi E, Csupor D. Penetration of lycopsamine from a comfrey ointment through human epidermis. Homeopathy. Begin mixing on low. Tanret, I. and Duh, D. [Pharmaceutical sheet. 4.3 4.3 out of 5 stars (225) $19.95 $ 19. MedlinePlus Medical Encyclopedia. Heard about essential oils but not quite sure about what they can do for you? Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. Comfrey oil shouldnt be used for cooking, like other types of cooking oil. Company number 02758955 Registered VAT number 211727395. Do not use this product without medical advice if you are breast-feeding a baby. Phytomedicine 2005;12(10):707-714. Registered VAT no. Which part of the comfrey plant has the lowest level of pyrrolizidine alkaloids (PAs)? Arzneimittelforschung. Beth Thomas, PharmD, is a clinical pharmacist and founder of BMT Consulting Services, LLC. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties Customer Reviews Ingredients Full ingredients Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). 2013;27(6):811-7. Eucalyptus oil is used externally to stimulate blood flow. Journal of chiropractic medicine, 10(3), 147-156. https://doi.org/10.1016/j.jcm.2011.01.003, Stam, C., Bonnet, M. S., & van Haselen, R. A. View abstract. Kucera, M., Kalal, J., and Polesna, Z. Wien Med Wochenschr. J Chiropr Med. Children, who suffer from these injuries the most, are statistically unlikely to have adverse reactions to comfrey oil when used on scrapes.5, When comfrey was applied topically to animals above where theyd suffered bone fractures, their bones healed at a much-improved rate than animals who hadnt been treated with comfrey.6, Leg ulcers are uncomfortable, prone to infection, and can take a long time to heal. View abstract. J Chin Med.Assoc. Comfrey (Symphytum officinale) is a plant with yellow or purple flowers found in Europe, Asia, and North America. A large review released in 2013 about the medicinal uses of comfrey stated: It is clinically proven to relieve pain, inflammation and swelling of muscles and joints in the case of degenerative arthritis, acute myalgia in the back, sprains, contusions and strains after . 2012;(1):41-42. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., Giannetti, B., Klingenburg, S., and Staiger, C. Efficacy and tolerance of a comfrey root extract (Extr. These include allantoin, rosmarinic acid, and others. Grube, B., Grunwald, J., Krug, L., and Staiger, C. Efficacy of a comfrey root (Symphyti offic. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Liver injury from herbal and dietary supplements. Can a comfrey (Symphytum officianale) root extraction help ease aching joints and muscles? Results of an observational study of patients]. Registered VAT no. Be sure to use comfrey root from a reputable source that has properly identified the species. Mazzocchi, A. and Montanaro, F. Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery. Potters Herbal Comfrey Oil is a soothing aromatic herbal massage oil. Its ready when the mixture has solidified somewhat and has a cloudy, creamy, and slightly runny consistency. However, further well-designed studies are needed. 2012;20(11):1209-1216. Documented adverse effects (the pyrrolizidine alkaloids, have substantial risk of causing fatal liver damage and can cause abortion). Rad. Newer Post Older . 2007;157(21-22):569-574. 2007;14(1):2-10. Arzneimittelforschung, 62(06), 285-289. https://doi.org/10.1007/s10354-007-0474-y, Giannetti, B. M., Staiger, C., Bulitta, M., & Predel, H. G. (2010). Knit bone, Eucalyptus, Rapeseed Oil, BHA. Ther Drug Monit 2001;23:698-708. A limited number of clinical trials show short-term efficacy of topically applied, alkaloid-free comfrey preparations in skin abrasions and inflammatory conditions. View abstract. Dietary Supplements: What You Need to Know. HTB; 2021 2; Youtube; Twitter; Facebook; ; Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). In a randomized, controlled, double-blind study with 203 patients, applications of a 10% comfrey cream were well tolerated, reduced swelling and pain, and improved mobility (Kucera et al., 2004). Written by Cerner Multum. Learn more in The Comfrey Controversy: Can and Should One Use Comfrey Internally? BMJ Case Rep. 2016. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties. Our Two Pennies Worth. Gyorik, S. and Stricker, H. Severe pulmonary hypertension possibly due to pyrrolizidine alkaloids in polyphytotherapy. No supplement is intended to treat, cure, or prevent disease. Be sure to choose organic carrier oils and essential oils when possible. Comfrey has been cultivated as a green vegetable and has been used as an herbal medicine for more than 2,000 years. This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

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