Venofer may cause clinically significant hypotension. Adult Patients with Hemodialysis Dependent-Chronic Kidney Disease (HDD-CKD): Administer Venofer 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Use Caution/Monitor. Iron deficit - equation derivation: Assumptions: -Blood volume = 65 mL/kg -Hemoglobin conc target =14.0 g/dL -Deficits in body stores are ignored. Monitor Closely (1)dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Use Caution/Monitor. Serious hypersensitivity reactions, including anaphylactic-type reactions, some of which have been life-threatening and fatal, have been reported in patients receiving Venofer. Other indications for IV are pregnancy iron deficiency, chronic renal impairment or need for rapid repletion. Minor/Significance Unknown. Separate by 2 hr. When iron sucrose was administered at deliberate overdoses to rabbit dams (up to 215 mg/kg/day) marked fetal/placental iron overload was noted. Ferrlecit may also be administered undiluted as a slow intravenous injection (at a rate of up to 12.5 mg/min) per dialysis session. Follow your doctor's directions carefully.Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft).A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. David McAuley, Pharm.D. . Use alternatives if available. Alternatively the total dose may be calculated: Dose (mL) = 0.0442 (Desired Hb - Observed Hb) x LBW + (0.26 x LBW) Based on: Desired Hb = the target Hb in g/dl. You will have to pay for your IV iron. Use Caution/Monitor. vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. 1988 May;111(5):566-70. The recommendation is that most adults need a cumulative dose of elemental iron of at least 1 g. Iron replenishment can be done intravenously, either as total dose (example: iron-dextran or iron carboxymaltose) or as split dose (example: iron sucrose). Applies only to oral form of both agents. This website also contains material copyrighted by 3rd parties. Minor/Significance Unknown. The initial hemoglobin rise is more rapid with parenteral iron but on the long term (12 weeks), both therapies reach similar levels of hemoglobin. This website is intended for use by US healthcare professionals only. Hemoglobin can be input in g/dL, g/L or mmol/L and refers to the amount of hemoglobin in the red blood cells. Applies only to oral form of both agents. LBW = Lean body weight in kg. Untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia. Below the form there are further instructions on how to use the calculator. trientine, iron sucrose. Venofer treatment may be repeated if necessary. prescription products. commonly, these are "non-preferred" brand drugs or specialty Your doctor will do laboratory tests to monitor your response. Use Caution/Monitor. Med J Aust; 193(9):525-32. PRECAUTIONS: Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Either increases effects of the other by pharmacodynamic synergism. Applies only to oral form of both agents. Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Use Caution/Monitor. In case a pediatric patient with a weight below 35 kg is assessed, iron stores are calculated as 15 mg iron for each kg. Use Caution/Monitor. Manage and view all your plans together even plans in different states. iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. Modify Therapy/Monitor Closely. Applies only to oral form of both agents. Avoid or Use Alternate Drug. )If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. View the formulary and any restrictions for each plan. This information does not assure that this product is safe, effective, or appropriate for you. Minor (2)calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Give each dose as 750mg for a total cumulative dose not to exceed1500mg of ironper course. Learn how to store and discard medical supplies safely. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. Applies only to oral form of both agents. Use Caution/Monitor. 1000 mg. 20 MINUTES. For iron maintenance treatment, administer Venofer, (2 years of age or older) with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment. Oral iron therapy is the first method while IV therapy comes in place when there are contraindications or the body doesnt respond to the oral one. Use Caution/Monitor. In key trials, ferric carboxymaltose increased Hb levels and replenished iron stores as effectively as IV iron sucrose . Applies only to oral form of both agents. Read our. 2010;18(3). Use Caution/Monitor. Monitor for signs and symptoms of hypotension following each Feraheme infusion. A maximum dose of 1000 mg iron can be delivered intravenously over 15 minutes, which may make it a suitable treatment for iron-deficiency anaemia outside of the hospital setting. VENOFER at IV doses up to 15 mg iron/kg/dose [about 10 times the maximum recommended human dose for a 70 kg person] given three times a week was found to have no effect on fertility . 1) Ganzoni AM. Applies only to oral form of both agents. Med J Aust. Official Journal of the International Society of Nephrology. To provide clinicians with evidence-based guidance for iron therapy dosing in patients with iron deficiency anemia (IDA), we conducted a study examining the benefits of a higher cumulative dose of intravenous (IV) iron than what is typically administered. Parenteral iron product is iron sucrose (C = 20 mg elemental iron/mL). Pediatric Patients: The most common adverse reactions (2%) are headache, respiratory tract viral infection, peritonitis, vomiting, pyrexia, dizziness, cough, nausea, arteriovenous fistula thrombosis, hypotension and hypertension. iron sucrose decreases levels of ibandronate by inhibition of GI absorption. Calculation of total iron deficit for initial repletion: [29] Total cumulative dose (mg) = [Target Hb Actual Hb] weight (kg) 2.4 + [15 weight (kg)] *Hb in g/dl: 2. Applies only to oral form of both agents. Use Caution/Monitor. Monitor Closely (1)nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Do Not Copy, Distribute or otherwise Disseminate without express permission. Although anaphylactic reactions known to occur following INFeD administration are usually evident within a few minutes, or sooner, it is recommended that a period of an hour or longer elapse before the remainder of the initial therapeutic dose is given. Option 2: 200 mg in NS 100 mL administered over 20-30 minutes; may repeat every other day to Avoid or Use Alternate Drug. The dosage of Venofer is expressed in mg of elemental iron. Venofer treatment may be repeated if iron deficiency reoccurs. Separate by 2 hr. March 2, 2015 [IRON SUCROSE REQUIREMENT CALCULATION FOR SEVERE ANEMIA] DPMU Anantapuramu | National Health Mission 1 Formula for calculating the required dose of Iron sucrose 2.4 X Pre-pregnancy Weight in Kgs X Hb% deficit{11-actual Hb%} in mgs Plus Iron required to replenish the iron stores = 500mg Prepregnancy Weight = 45 kgs . Use Caution/Monitor. Fatal reactions have followed the test dose of iron dextran injection. In: Koda-Kimble & Young's Applied Therapeutics: The Clinical Use of Drugs. ibuprofen/famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Do not double the dose to catch up. Copyright 2021 GlobalRPH - Web Development by. Venofer® (iron sucrose) injection, USP is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Interaction only with oral iron administration. In less advanced cases of iron deficiency, increases in dietary intake of iron may be sufficient. sodium bicarbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Avoid or Use Alternate Drug. Monitor Closely (1)cimetidine will decrease the level or effect of iron sucrose by increasing gastric pH. iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. Anemia. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Avoid or Use Alternate Drug. Interaction only with oral iron administration. iron sucrose increases levels of calcium chloride by enhancing GI absorption. Avoid or Use Alternate Drug. Your doctor will do laboratory tests to monitor your response. Applies only to oral form of both agents. Both the 200- and 300-mg doses of IV iron sucrose administered over 2 hours appear to be safe. Copyright 2021 GlobalRPH - Web Development by, Calculation of the Total Iron Deficit Alternative equation. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. Then enter the value of the Dosage and choose the unit of measurement from the drop-down menu. 5. Avoid or Use Alternate Drug. Due Date form Ultrasound Report. Philadelphia, PA: Lippincott Williams & Wilkins;2013;303-307. Applies only to oral form of both agents. Use Caution/Monitor. Administer Venofer only intravenously by slow injection or by infusion. Individual plans may vary Avoid or Use Alternate Drug. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Deferoxamine chelates iron. 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Minor/Significance Unknown. Monitor Closely (1)iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. All adult and pediatric patients receiving Venofer require periodic monitoring of hematologic and iron parameters (hemoglobin, hematocrit, serum ferritin and transferrin saturation). Avoid or Use Alternate Drug. Either increases effects of the other by pharmacodynamic synergism. The dosage of iron sucrose is expressed in mg of elemental iron. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Applies only to oral form of both agents. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. All Rights Reserved. Human studies not conducted. Venofer is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Applies only to oral form of both agents. Applies only to oral form of both agents. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Minor (1)iron sucrose, captopril. Monitor Closely (1)deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. 2. Minor (1)iron sucrose decreases levels of manganese by inhibition of GI absorption. DOSAGE AND ADMINISTRATION: Oral iron should be discontinued prior to administration of INFeD. You may report side effects to Health Canada at 1-866-234-2345. Reference www.medicines.org.uk Background Normal haemoglobin values are gender specific: for males from 13.8 to 18.0 g/dL (138 to 180 g/L, or 8.56 to 11.17mmol/L) and females from 12.1 to 15.1 g/dL (121 to 151 g/L, or 7.51 to 9.37mmol/L). If you log out, you will be required to enter your username and password the next time you visit. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Most Administer Feraheme as an intravenous infusion in 50-200 mL 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP over at least 15 minutes. Applies only to oral form of both agents. Use Caution/Monitor. The weight of the patient is taken into account in order to estimate iron stores, while haemoglobin is required as both current measured and target. The factor 2.4 comes about from the calculation that the total iron content of hemoglobin is 0.34%, the blood volume accounts for 7% . All Rights Reserved. Use Caution/Monitor. Fatal reactions have also occurred in situations where the test dose was tolerated. Deferiprone may bind polyvalent cations (eg, iron, aluminum, and zinc), separate administration by at least 4 hr between deferiprone and other medications (eg, antacids), or supplements containing these polyvalent cations. Copyright(c) 2023 First Databank, Inc. Applies only to oral form of both agents. Minor (2)calcium chloride decreases levels of iron sucrose by inhibition of GI absorption. Most reactions associated with intravenous iron preparations occur within 30 minutes of the completion of the infusion. Dosing for patients who weigh 50 kg or more For patients weighing 50 kg (110 lb) or more: Give Injectafer in two doses separated by at least 7 days. calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. HOW TO USE: This medication is given by injection into a vein as directed by your doctor. Allow at least 30 minutes between administration of Feraheme and administration of other medications that could potentially cause serious hypersensitivity reactions and/or hypotension, such as chemotherapeutic agents or monoclonal antibodies. Accessed: 4/12/2011. commonly, these are "preferred" (on formulary) brand drugs. Applies only to oral form of both agents. an automated flowchart approach. Monitor Closely (1)calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Creating an account is free and takes less than 1 minute. iron sucrose increases levels of calcium acetate by enhancing GI absorption. Minor/Significance Unknown. 1990 Feb;24(2):162-6. Avoid or Use Alternate Drug. Parenteral iron dextran therapy. Hanson DB, Hendeles L. Guide to total dose intravenous iron dextran therapy. Applies only to oral form of both agents. Recommended starting dose 1 Aranesp is dosed at 2.25 mcg/kg SC QW or 500 SC Q3W 1 (SC = subcutaneous) Before initiating 1: Evaluate iron status; administer supplemental iron therapy as needed Correct or eliminate other causes of anemia Initiate 1: Only when Hb < 10 g/dL Pediatric Patients (2 Years of Age and Older). Volume of iron sucrose needed = 60 x (14 - 8) x (2.145) 20 = 38.6 mL . No additional iron to replenish stores. Am J Kid Dis 2001; 38 988991. Human studies not conducted. 1996 Aug;11(4):139-46. 4) Gozzard D. (2011) When is high-dose intravenous iron repletion needed? commonly, these are generic drugs. Separate dosing of tetracyclines from these products. Use Caution/Monitor. Minor (2)calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Most adults require a cumulative dose of elemental iron of at least 1 g. Iron replenishment is usually doneintravenously, via iron-dextran, iron sucrose or iron carboxymaltose. Patients with a history of drug allergy or multiple drug allergies may be at increased risk of anaphylactic-type reactions to INFeD. Avoid or Use Alternate Drug. For repletion treatment most patients may require a cumulative dose of 1000 mg of elemental iron administered over 8 dialysis sessions. Applies only to oral form of both agents. esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. IDA diagnosis is based on full blood examination and on the serum ferritin level. (1970) Intravenous iron-dextran: therapeutic and experimental possibilities. Applies only to oral form of both agents. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 - Hb in g/dL) x 2.145 Volume of product required in mL = Iron deficit in mg / C in mg/mL Where C is the concentration of the iron product: 50 mg/mL for Iron dextran; 20 mg/mL for Iron sucrose; 5 mg/mL for Ferric gluconate. The primary endpoint was the proportion of patients with . David McAuley, Pharm.D. Diagnosis and management of iron deficiency anaemia: a clinical update. Ferrlecit has been administered at sequential dialysis sessions by infusion or by slow intravenous injection during the dialysis session itself. iron sucrose decreases levels of eltrombopag by inhibition of GI absorption. Use alternatives if available. Iron sucrose: 20 mg/mL. Intravenous Injection - PRIOR TO THE FIRST INTRAVENOUS INFeD THERAPEUTIC DOSE, ADMINISTER AN INTRAVENOUS TEST DOSE OF 0.5 ML. Mean change in Hgb from baseline to Week 5 2,5 Ferrlecit may be diluted in 100 mL of 0.9% sodium chloride administered by intravenous infusion over 1 hour per dialysis session. The usual adult total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Parenteral iron dextran therapy: a review. however iron sucrose requires multiple small intermittent doses over days to weeks. . Iron Deficiency Anemia: Periodic hematologic determination (hemoglobin and hematocrit) is a simple and accurate technique for monitoring hematological response, and should be used as a guide in therapy. Avoid or Use Alternate Drug. 2 *Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with CKD. Data from Ferrlecit postmarketing spontaneous reports indicate that individual doses exceeding 125 mg may be associated with a higher incidence and/or severity of adverse events. calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Either decreases levels of the other by inhibition of GI absorption. Serious - Use Alternative (1)iron sucrose decreases levels of eltrombopag by inhibition of GI absorption. Anemia caused by the depletion of iron is called iron deficiency anemia. Monitor Closely (1)sodium citrate/citric acid will decrease the level or effect of iron sucrose by increasing gastric pH. Minor/Significance Unknown. Administer on 5 different occasions over a 14 day period. Use Caution/Monitor. In a randomized, open-label, dose-ranging trial for iron maintenance treatment with Venofer in pediatric patients with CKD on stable erythropoietin therapy [see Clinical Studies ( 14.7)], at least one adverse reaction was experienced by 57% (27/47) of the patients receiving Venofer 0.5 mg/kg, 53% (25/47) of the patients receiving Venofer 1 mg . Compare formulary status to other drugs in the same class. For patients receiving hemodialysis, administer Feraheme once the blood pressure is stable and the patient has completed at least one hour of hemodialysis. Where: Medicine concentration Amount of active substance per a given volume of your drug. Monitor Closely (1)iron sucrose decreases levels of liothyronine by inhibition of GI absorption. Koch TA, Myers J, Goodnough LT. Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Modify Therapy/Monitor Closely. Intermediate calculations: -Blood volume (dL) = [65 (mL/kg) x body weight (kg)] / 100 (mL/dL) -Hgb deficit (g/dL) = 14.0 - patient hgb conc. The dosage of Venofer is expressed in mg of elemental iron. Applies only to oral form of both agents. The total amount of INFeD in mL required to treat the anemia and replenish iron stores may be approximated as follows: Adults and Children over 15 kg (33 lbs): See Dosage Table. World J Gastroenterol; 16(22): 27202725. Venofer may reduce the absorption of concomitantly administered oral iron preparations. 2 DOSAGE & ADMINISTRATION Venofer must only be administered intravenously either by slow injection or by infusion. Observed Hb = the patients current hemoglobin in g/dl. Use Caution/Monitor. The dosing for iron replacement treatment in pediatric patients with NDD-CKD or PDDCKD has not - been established. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Assessing new treatment options. Nutr Clin Pract. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. 2.1 Dosage - Total dose infusion The dose calculation for CosmoFer is based on patients body weight according to the table below and is diluted in 500mLs of normal saline. iron sucrose decreases levels of minocycline by inhibition of GI absorption. iron sucrose increases levels of calcium gluconate by enhancing GI absorption. Discuss the risks and benefits with your doctor.This medication passes into breast milk. I. Use Caution/Monitor. Serum iron, total iron binding capacity (TIBC) and percent saturation of transferrin are other important tests for detecting and monitoring the iron deficient state. Next Steps Evidence Creator Insights Dr. Andreas M. Ganzoni About the Creator Kidney Int. Hollands J, Foote E, Rodriguez A. Before using, check this product visually for particles or discoloration. DICP. J Med. Pregnancy: Risk Summary-Clinical Considerations. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. If no signs or symptoms of anaphylactic-type reactions follow the test dose, administer the full therapeutic INFeD dose. Applies only to oral form of both agents. Applies only to oral form of both agents. In post-marketing safety studies of Venofer in 1,051 patients with HDD-CKD, adverse reactions reported by >1% were cardiac failure congestive, sepsis and dysgeusia. Ferumoxytol [ Feraheme ] Elemental iron: 510 mg/17 mL (17 mL) 30 mg/mL [package insert] - Boxed warning REVIEW INSERT. Recommended dosage for patients weighing less than 50kg (110lb): Give Injectafer in Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Calculation of the Total Iron Deficit Alternative equation, Iron Dextran Dosing Calculator (iron deficit), HONcode standard for trust- worthy health, Pediatric Oncology: Diagnosis And Prognosis Communication, Pharmacosmos A/S, CosmoFer low molecular weight (Mw) iron dextran. Avoid or Use Alternate Drug. FERAHEME met the predefined criteria for non-inferiority to Venofer . Contraindicated. You can further save the PDF or print it. It should be recognized that iron storage may lag behind the appearance of normal blood morphology. The recommended dosage of iron sucrose for repletion of iron deficiency in patients undergoing hemodialysis is 5ml of iron sucrose (100mg of elemental iron) delivered intravenously during the dialysis session. sodium citrate/citric acid will decrease the level or effect of iron sucrose by increasing gastric pH. Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products (such as Venofer) which may cause fetal bradycardia, especially during the second and third trimester. Minor/Significance Unknown. Use Caution/Monitor. 1970;100(7):301303. Calculosaurus | Medical calculators for obstetrics and gynaecology Use the menu to browse through our clinical calculators. Serious - Use Alternative (1)iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Monitor Closely (1)aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Properly discard this product when it is expired or no longer needed. Applies only to oral form of both agents. Applies only to oral form of both agents. calcium gluconate decreases levels of iron sucrose by inhibition of GI absorption. Equations : Total body iron deficit (mg) = body weight (kg) x (target Hb - actual Hb in g/dL) x 2.4 + iron depot (mg)** [1, 2] Iron depot: 15 mg/kg for body weight less than 35 kg 500 mg for those with a body weight greater than or equal to 35 kg Ideal Body Weight (kg) =45.5 +2.3 * (height inches - 60 inches) [3] Initial symptoms may include hypotension, syncope, unresponsiveness, cardiac/cardiorespiratory arrest. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time.Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Crown Rump Length and Nuchal Translucency. IDA symptoms are often nonspecific and include tiredness, weakness, shortness of breath. Where C is the concentration of the iron product: Please note that the calculations above are for information purposes only and the individual dose needs to be established by taking into account the current package insert for the elemental iron product used. Applies only to oral form of both agents. Injection: 50 mg/2.5 mL, 100 mg/5 mL, or 200 mg/10 mL (20 mg/mL) in single-dose vials. Applies only to oral form of both agents. Last updated 28/06/2018 Enter values here and press 'Calculate'. Minor/Significance Unknown.iron sucrose increases levels of calcium gluconate by enhancing GI absorption. Monitor Closely (1)famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Monitor patients for signs and symptoms of hypersensitivity during and after Venofer administration for at least 30 minutes and until clinically stable following completion of the infusion. Iron deficiency anemia calculator (diagnosis), Iron deficiency anemia vs. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Diagnosis and management of iron deficiency anaemia: a clinical update. Echocardiogram Z Score (NEW)(BETA TESTING) Edinburgh Postnatal Depression Scale. . The Ganzoni equation used by the iron deficiency calculator is the following: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores. *Administer early during the dialysis session. USES: This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Monitor Closely (1)ibuprofen/famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Elemental iron product this is a choice between three iron supplement products: Iron dextran 50 mg/mL, Iron sucrose 20 mg/mL and Ferric gluconate 12.5 mg/mL. Applies only to oral form of both agents. Use Caution/Monitor. lansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Parenteral Iron Replacement For Iron Deficiency Anemia Calculator, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Clinical use of the total dose intravenous infusion of iron dextran, When is high-dose intravenous iron repletion needed? During all INFeD administrations, observe for signs or symptoms of anaphylactic-type reactions. Applies only to oral form of both agents. Monitor Closely (1)vitamin E decreases levels of iron sucrose by increasing hepatic clearance. iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Serious - Use Alternative (1)iron sucrose decreases levels of ciprofloxacin by inhibition of GI absorption. Use Caution/Monitor. Then you can click on the Print button to open a PDF in a separate window with the inputs and results. Minor/Significance Unknown. Iron deficiency anemia is the type of anemia caused by iron depletion. The recipient will receive more details and instructions to access this offer. Serious - Use Alternative (1)iron sucrose decreases levels of doxycycline by inhibition of GI absorption.
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